| External data extracted from UniProtKB/Swiss-Prot |
| Extracted from UniProtKB/Swiss-Prot, release: 0.0 |
| Entry name | CRLF3_HUMAN |
| Primary accession number | Q8IUI8 |
| Secondary accession number(s) | A6NJF3 B2R8C3 Q2MLY7 Q9UNI3 Q9Y6M8 |
| Sequence was last modified on | March 1, 2004 (version 2) |
| Annotations were last modified on | March 15, 2017 (version 126) |
| Name and origin of the protein |
| Description | RecName: Full=Cytokine receptor-like factor 3; AltName: Full=Cytokine receptor-like molecule 9; Short=CREME-9; AltName: Full=Cytokine receptor-related protein 4; AltName: Full=Type I cytokine receptor-like factor p48; |
| Gene name | Name=CRLF3 Synonyms=CREME9, CRLM9, CYTOR4, P48 |
| Encoded on | Name=CRLF3; Synonyms=CREME9, CRLM9, CYTOR4, P48 |
| Keywords | Acetylation; Alternative splicing; Coiled coil; Complete proteome; Cytoplasm; Polymorphism; Reference proteome. |
| Copyright |
| Copyrighted by the UniProt Consortium, see http://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License |
| Cross-references |
| EMBL | DQ298450; ABC55264.1; -; mRNA |
| EMBL | AF046059; AAD02422.1; -; mRNA |
| EMBL | AF120151; AAD31758.1; -; mRNA |
| EMBL | AK313315; BAG36120.1; -; mRNA |
| EMBL | AC127024; -; NOT_ANNOTATED_CDS; Genomic_DNA |
| EMBL | BC023567; AAH23567.2; -; mRNA |
| CCDS | CCDS32607.1; -. [Q8IUI8-1]; . |
| RefSeq | NP_057070.3; NM_015986.3. [Q8IUI8-1]; . |
| UniGene | Hs.649372; -; . |
| ProteinModelPortal | Q8IUI8; -; . |
| SMR | Q8IUI8; -; . |
| BioGrid | 119511; 16; . |
| IntAct | Q8IUI8; 18; . |
| STRING | 9606.ENSP00000318804; -; . |
| iPTMnet | Q8IUI8; -; . |
| PhosphoSitePlus | Q8IUI8; -; . |
| BioMuta | CRLF3; -; . |
| DMDM | 74762472; -; . |
| OGP | Q9Y6M8; -; . |
| EPD | Q8IUI8; -; . |
| MaxQB | Q8IUI8; -; . |
| PaxDb | Q8IUI8; -; . |
| PeptideAtlas | Q8IUI8; -; . |
| PRIDE | Q8IUI8; -; . |
| DNASU | 51379; -; . |
| Ensembl | ENST00000324238; ENSP00000318804; ENSG00000176390. [Q8IUI8-1]; . |
| GeneID | 51379; -; . |
| KEGG | hsa:51379; -; . |
| UCSC | uc002hfr.5; human. [Q8IUI8-1]; . |
| CTD | 51379; -; . |
| DisGeNET | 51379; -; . |
| GeneCards | CRLF3; -; . |
| HGNC | HGNC:17177; CRLF3; . |
| HPA | HPA007596; -; . |
| MIM | 614853; gene; . |
| neXtProt | NX_Q8IUI8; -; . |
| OpenTargets | ENSG00000176390; -; . |
| PharmGKB | PA26884; -; . |
| eggNOG | ENOG410II83; Eukaryota; . |
| eggNOG | ENOG4110NSY; LUCA; . |
| GeneTree | ENSGT00390000014117; -; . |
| HOGENOM | HOG000111973; -; . |
| HOVERGEN | HBG054457; -; . |
| InParanoid | Q8IUI8; -; . |
| OMA | DYRLQYR; -; . |
| OrthoDB | EOG091G0GM2; -; . |
| PhylomeDB | Q8IUI8; -; . |
| TreeFam | TF328682; -; . |
| ChiTaRS | CRLF3; human; . |
| GeneWiki | CRLF3; -; . |
| GenomeRNAi | 51379; -; . |
| PRO | PR:Q8IUI8; -; . |
| Proteomes | UP000005640; Chromosome 17; . |
| Bgee | ENSG00000176390; -; . |
| CleanEx | HS_CRLF3; -; . |
| ExpressionAtlas | Q8IUI8; baseline and differential; . |
| Genevisible | Q8IUI8; HS; . |
| GO | GO:0005737; C:cytoplasm; IDA:UniProtKB; . |
| GO | GO:0005829; C:cytosol; IDA:HPA; . |
| GO | GO:0005886; C:plasma membrane; IDA:HPA; . |
| GO | GO:0042802; F:identical protein binding; IPI:IntAct; . |
| GO | GO:0000082; P:G1/S transition of mitotic cell cycle; IMP:UniProtKB; . |
| GO | GO:0030308; P:negative regulation of cell growth; IDA:UniProtKB; . |
| GO | GO:0071158; P:positive regulation of cell cycle arrest; IDA:UniProtKB; . |
| GO | GO:0046427; P:positive regulation of JAK-STAT cascade; IDA:UniProtKB; . |
| GO | GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB; . |
| GO | GO:0045893; P:positive regulation of transcription; DNA-templated; IDA:UniProtKB |
| CDD | cd00063; FN3; 1; . |
| Gene3D | 2.60.40.10; -; 1; . |
| InterPro | IPR003961; FN3_dom; . |
| InterPro | IPR013783; Ig-like_fold; . |
| SUPFAM | SSF49265; SSF49265; 1; . |
| PROSITE | PS50853; FN3; 1; . |